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Twelve people awaken in a strange house with no phone, and no exits - they are completely shut out from the outside world. They do not know each other...they don't even remember who they are themselves. An observer comes over an intercom to tell them they all volunteered for a unique sociological experiment: their memories have been blocked, and they are to live for the next year in this enclosed house. But there is a catch: one of them was a convicted killer prior to the induced amnesia. The study is specifically aimed at whether murderous intent is learned or innate. Out of necessity they begin to build relationships and allegiances only to find the trust and cooperation begins to deteriorate once people begin to die. The group continuously battles distrust and panic, and the social order breaks down again and again threatening more lives and the thin layer of cohesion the group desperately needs to survive.