From the bestselling author of The Plague Tales comes a new novel that sweeps from medieval France to America in the year 2007. In fourteenth-century France, pockets of plague still bring death to peasants and noblemen alike. Amid the fury and the chaos, Dr. Alejandro Canches searches for a safe haven, accompanied by his foster child, Kate.But both disease and human enemies pursue them, and their only hope for survival is a rebel leader. Seven hundred years later, Dr. Janie Crowe is searching for the cure for a crippling disease in a world where genetic engineering has gone mad. A repressive government wants to stop her, unnamed benefactors want to help her, and time is running out to find answers linking two dark eras.