When an experimental space voyage goes awry, four people are forever changed by cosmic radiation. Scientist Reed Richards; his ex-girlfriend, Sue Storm; his best friend, Ben Grimm; and Sue's younger brother, Johnny, experience mutagenic changes. Together they use their new powers to rid the world of evil. These forces may benefit society, but the Fantastic Four are struggling to adapt to their new lives as superheroes. Will Mr. Fantastic, the Invisible Woman, the Thing, and the Human Torch be able to foil Doctor Doom's evil plot?